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Medical Notes: Week of June 3, 2018

A new link between specific genes and depression, the potential to use a certain protein to treat sundown syndrome in Alzheimer’s patients, and new research on an increased risk of death after the death of a spouse.

You are here: Home / Archive / Medical Notes / Medical Notes: Week of June 3, 2018
Published: June 3, 2018 by RHJ Producer

Scientists have long sought the genetic connections to depression, and a major new study has found several dozen of them. The study in the journal Nature Genetics has identified 44 genomic variants associated with depression…30 of them totally new discoveries. Researchers say the more of these variants a person has, the more likely they are to have depression. Many of the genes are also linked to other disorders such as schizophrenia, bipolar disorder, obesity, and sleep disorders. Scientists call the study a “game changer.”

Every day when the sun sets, about 20% of Alzheimer’s patients suffer increased anxiety, disorientation, irritation and aggression. But now scientists have located the brain pathway causing “sundown syndrome,” at least in mice, and have developed a way to shut it down. They say the circadian rhythm disorder in humans is very similar and they hope to use the protein tool they’ve developed to stop the disorder in mice in the same way.

And finally… when someone loses a spouse, they’re more than 40% more likely to die in the next six months. And now researchers have figured out at least part of the reason. A study in the journal Psychoneuroendocrinology shows that in the first three months of becoming a widow or widower, levels of pro-inflammatory cytokines rise significantly in the bloodstream while heart rate variability goes down. Both are connected with cardiac events and could help explain why it really is possible to die of a broken heart.

Program #: 18-22Segment Type: Medical NotesTopics: Anxiety and Depression| Cardiology| DNA and Genetics| Family and Interpersonal Relationships| Mental Health| News and Headlines| Research and Clinical TrialsMedical Conditions: Alzheimer's Disease and Dementia| Cardiovascular/Heart Disease| DepressionMedical Journals: Nature| Nature Genetics| Psychoneuroendocrinology
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About RHJ Producer

Since 1992, Radio Health Journal has been bringing listeners useful, verifiable information they can trust and rely on in the fields of medicine, science & technology, research, and the intersection of health & public policy. Both Radio Health Journal and sister show Viewpoints Radio are AURN productions.

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